Effect of apple extracts on mice lipid metabolism
date:2011-12-05
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Herbridge, 5 Dec. 2011_Apple extracts may help reduce blood lipid through adjustment of lipid metabolism, shows a new study published in the journal Science and Technology of Food Industry.

The random, controlled study was operated by researchers from Institute of Natural Resources of Heilongjiang Academy of Sciences, School of Forestry Northeast Forestry University and School of Food Science and Engineering of Harbin Institute of Technology. 60 mice were divided into 5 groups randomly. Except normal control group,the other four groups were fed high fat diet for 4 weeks. Normal control and obesity control groups were fed i.g.normal saline,the other three groups were fed i.g.38,76 and 114g/kg.bw apple extracts. After 4 weeks, the mice body weight,the content of serum total triglycerides(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),malondialdehyde(MDA),the activity of superoxide dismutase(SOD),glutathione peroxidase(GSH-PX),hepatic lipase(HL)and lipoprotein lipase(LPL)were assayed.

Results:Apple extracts could obviously reduce the mice body weight,the content of TG,TC,low density lipoprotein cholesterol(LDL-C)and MDA,and atherosclerosisdisease index(AI). It could also improve HDL-C and the activity of SOD,GSH-PX,HL and LPL in their blood serum. Researchers conclued that apple extracts have the benefits to reduce blood lipid in mice.

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